Cardiogen
What do these badges mean?
Evidence tier
- AHuman-validated — Human trials showing positive results and good safety.
- BAnimal-grade — No human trials yet, but solid animal/preclinical evidence of effect and safety.
- CAnecdotal — No human or animal trials — only anecdotal/observational reports.
- DInsufficient evidence — No or insufficient evidence (encyclopedia only — never recommended by the builder).
Safety light
- 🟢 Green — Only mild, manageable side effects; reasonable safety data.
- 🟡 Yellow — Needs active management, has a meaningful contraindication/interaction, or has thin long-term data.
- 🔴 Red — Risk of a hospital-level event — treat with serious caution.
Browse-only — not on the protocol builder's curated shortlist, so the builder won't recommend it.
What is it?
Cardiogen is a Khavinson bioregulator peptide targeting cardiomyocytes — claimed, like the rest of the family, to modulate gene expression for cardiac contractility and tissue maintenance. It’s part of the vascular/cardiovascular corner of the Khavinson short-peptide bioregulator family, alongside Vesugen.
What does it do in my body?
Like the rest of the Khavinson family, Cardiogen’s claimed mechanism is that a short tissue-derived peptide crosses cell and nuclear membranes, binds DNA promoter regions, and modulates transcription in a tissue-specific way — here, in cardiac tissue. There is no Cardiogen-specific mechanism data beyond this general family-level theoretical claim; the family’s underlying nuclear-penetration mechanism has in-vitro support (Fedoreyeva et al. 2011, Biochemistry (Mosc), 22117547), but that work was not done on Cardiogen specifically.
How can it help me?
- Where the science stands: Directory lists “Moderate” (12 studies, 9 human) — but the 9 human studies are a citation-mismatch, not real peptide evidence. Actual base: preclinical/anecdotal
The full evidence — every human, animal, and lab study, graded — is one tap away: use the See the deeper science → toggle at the top.
Is it dangerous? What are the side effects?
No Cardiogen-specific adverse-event data exists. The family-wide reported profile in the Russian literature is mild and uncommon: occasional injection-site reactions, transient mild headache early in a cycle.
The real risk isn’t the molecule — it’s the supply chain. Khavinson-family peptides are the dominant gray-market counterfeit category in the peptide space, and Cardiogen’s thin evidence base makes it an even easier target for mislabeling since there’s little independent literature to check a seller’s claims against. Third-party COA verification matters more here than for almost any other peptide class.
Regulatory status: Cardiogen is research_only in the US — not FDA-approved for human use, sold as a research compound, not eligible for compounding. It is not a controlled substance. Unlike Thymalin, Cardiogen holds no clinical-use approval anywhere.
Part 1 — How to reconstitute it
What you'll need: bacteriostatic water (sterile, preserved water you mix the powder with) and a separate, larger reconstitution syringe just for mixing — not the small syringe you inject with.
The exact bacteriostatic-water volume and resulting concentration for Cardiogen are covered in the dosing notes and the deeper-science view. Confirm the right volume for your vial before mixing.
How to mix it
- Tilt the vial and let the bacteriostatic water run slowly down the inside glass wall — never squirt it straight onto the powder.
- Swirl gently to dissolve. Never shake — shaking can damage the peptide.
- Store the reconstituted vial refrigerated and out of light.
- Use it within the beyond-use window your source specifies — reconstituted peptides are commonly used within a few weeks; confirm the window for your specific peptide.
Use the free reconstitution calculator to turn any vial size + water volume into exact units on an insulin syringe.
Part 2 — Typical dosing
Talk to your medical provider before starting any protocol. That said, here are the doses most people commonly use — shared for educational purposes so you can have an informed conversation. These peptides are sold for research use only and are not FDA-approved drugs, and this isn't medical advice.
The syringe. Use a 0.3 mL U-100 insulin syringe — it's sized for these small subcutaneous doses. Inject subcutaneously (into the fat just under the skin) and rotate injection sites.
Educational purposes only — this reflects what the Russian-school protocol convention and the peptide community actually use, stated plainly; it is not medical advice.
There is no Western-validated dosing protocol for Cardiogen, and — unlike some other provisional members — no meaningful clinical or community dosing record either, given the thin evidence base. What exists is only the generic Khavinson-family cycle pattern:
- Cycle structure: a short course — typically 10–20 consecutive days — followed by a long rest, repeated 2–3 times per year, per the broader family convention.
- Dose: synthetic Khavinson short peptides generally converge around ~100–200 mcg/day over the cycle, but no Cardiogen-specific dose-finding data exists to confirm this applies here.
- Storage: lyophilized powder is stable cold; once reconstituted with bacteriostatic water, refrigerate and use within roughly 28 days.
Treat any specific number for Cardiogen as generic family convention, not peptide-specific validated dosing.
Turning milligrams into syringe units. On a U-100 syringe, 100 units = 1 mL, so 1 unit = 0.01 mL. At a concentration of C mg/mL, a dose of D mg = D ÷ C mL = (D ÷ C) × 100 units. Example: at 5 mg/mL, a 0.5 mg dose = 0.1 mL = 10 units. Your exact units depend on your own vial's mg and how much bacteriostatic water you added — use the same concentration you mixed above.
What should I avoid combining — and what's synergistic?
Cardiogen doesn't have a dedicated stacking protocol in our notes — the interactions that matter most are in the safety section above. For how people combine it with other peptides, the deeper-science view has the full detail.
How can I buy this?
Cardiogen is available from BioLongevity Labs — use code OHM-15 at BioLongevity for 15% off. As always, buy only from a source that publishes third-party Certificates of Analysis (COAs) confirming identity and >99% purity.
When you use my coupon code to buy peptides with these sellers, you enjoy a discount off retail price, and I make a small commission which helps me to continue to offer this peptide educational site to you for free. I only have affiliate relationships with peptide manufacturers that show evidence that their peptides are 100% manufactured in the US, 3rd party lab tested for purity, transparent COAs posted on their websites, and that have good customer service.
Cardiogen is a Khavinson bioregulator peptide targeting cardiomyocytes — but the “9 human studies” a source directory attaches to it are a citation-mismatch artifact, not real evidence for this peptide. Read that correction before anything else here; it’s the honesty-critical fact about this compound.
| Class | Khavinson bioregulator peptide targeting cardiomyocytes; sequence |
| Mechanism (one line) | Claimed to modulate gene expression for cardiac contractility and tissue maintenance |
| Evidence base | Directory lists “Moderate” (12 studies, 9 human) — but the 9 human studies are a citation-mismatch, not real peptide evidence. Actual base: preclinical/anecdotal |
| Safety record | No documented AEs specific to Cardiogen beyond the family-wide mild profile; OHM grade D / provisional |
| Regulatory status | research_only in the US, not FDA-approved |
What it is
Cardiogen is a Khavinson bioregulator peptide targeting cardiomyocytes — claimed, like the rest of the family, to modulate gene expression for cardiac contractility and tissue maintenance. It’s part of the vascular/cardiovascular corner of the Khavinson short-peptide bioregulator family, alongside Vesugen.
How it works
Like the rest of the Khavinson family, Cardiogen’s claimed mechanism is that a short tissue-derived peptide crosses cell and nuclear membranes, binds DNA promoter regions, and modulates transcription in a tissue-specific way — here, in cardiac tissue. There is no Cardiogen-specific mechanism data beyond this general family-level theoretical claim; the family’s underlying nuclear-penetration mechanism has in-vitro support (Fedoreyeva et al. 2011, Biochemistry (Mosc), 22117547), but that work was not done on Cardiogen specifically.
What the research shows
Important source caveat. The directory’s “9 human studies” figure for Cardiogen is not about the peptide at all — it’s about “CardioGen-82,” a rubidium-82 PET imaging generator, plus an unrelated Hungarian “Szeged CardioGen” cardiomyopathy registry (e.g. 28110572, 22393230). This is a directory auto-matching artifact, not real Cardiogen-peptide evidence.
The honest read: the Cardiogen peptide itself has no meaningful human evidence base. Treat the site’s “Moderate / 9 human” grade as spurious — the peptide sits at the preclinical/anecdotal level like the rest of the provisional set, not at “Moderate.” This is flagged and corrected here rather than repeated.
OHM grade: D / provisional — encyclopedia-only.
Real-world protocol
Educational purposes only — this reflects what the Russian-school protocol convention and the peptide community actually use, stated plainly; it is not medical advice.
There is no Western-validated dosing protocol for Cardiogen, and — unlike some other provisional members — no meaningful clinical or community dosing record either, given the thin evidence base. What exists is only the generic Khavinson-family cycle pattern:
- Cycle structure: a short course — typically 10–20 consecutive days — followed by a long rest, repeated 2–3 times per year, per the broader family convention.
- Dose: synthetic Khavinson short peptides generally converge around ~100–200 mcg/day over the cycle, but no Cardiogen-specific dose-finding data exists to confirm this applies here.
- Storage: lyophilized powder is stable cold; once reconstituted with bacteriostatic water, refrigerate and use within roughly 28 days.
Treat any specific number for Cardiogen as generic family convention, not peptide-specific validated dosing.
Side effects & management
No Cardiogen-specific adverse-event data exists. The family-wide reported profile in the Russian literature is mild and uncommon: occasional injection-site reactions, transient mild headache early in a cycle.
The real risk isn’t the molecule — it’s the supply chain. Khavinson-family peptides are the dominant gray-market counterfeit category in the peptide space, and Cardiogen’s thin evidence base makes it an even easier target for mislabeling since there’s little independent literature to check a seller’s claims against. Third-party COA verification matters more here than for almost any other peptide class.
Regulatory status
Cardiogen is research_only in the US — not FDA-approved for human use, sold as a research compound, not eligible for compounding. It is not a controlled substance. Unlike Thymalin, Cardiogen holds no clinical-use approval anywhere.
Sources
- primary profile (thepeptidelist.com directory capture, 2026-06-07).
- 0035 tier/safety/goal grading: Cardiogen kept D-provisional / encyclopedia-only.
- Name-collision PMIDs (NOT peptide evidence — flagged, not real citations for Cardiogen): 28110572, 22393230 (CardioGen-82 rubidium-PET / Szeged cardiomyopathy registry).
- Related: Vesugen · the Khavinson bioregulator family.
Sources & references
- primary profile (thepeptidelist.com directory capture, 2026-06-07).
- 0035 tier/safety/goal grading: Cardiogen kept D-provisional / encyclopedia-only.
- Name-collision PMIDs (NOT peptide evidence — flagged, not real citations for Cardiogen): 28110572, 22393230 (CardioGen-82 rubidium-PET / Szeged cardiomyopathy registry).
- Related: Vesugen · the Khavinson bioregulator family.